PXD065563 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | A proteomic view of butterfly morphogenesis |
| Description | Insect metamorphosis is one of the most fascinating developmental processes in the natural world. Complete metamorphosis requires the breakdown and re-organization of larval tissues, and the coordinated construction and development of adult structures. The molecular events that achieve this transformation are however incompletely understood, and there is in particular a shortage of data describing changes in protein abundance that occur during the metamorphic journey. Here we provide data from a proteomic analysis of consecutive developmental stages of a laboratory butterfly as it develops from a caterpillar into an adult via pupation. This provides a dynamic reference dataset representing 2749 detected proteins. Statistical analysis identified 90 proteins changing significantly in abundance during metamorphosis, and functional interpretation highlights cuticle formation, apoptosis and autophagy during the pupal stages, and the up-regulation of respiration and energy metabolism upon emergence of the fully formed adult. A search for peptide phosphorylation modifications in the data identified three proteins with roles in muscle function suggesting developmental stage-dependent phosphorylation events. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-01-05 |
| AnnouncementXML | Submission_2026-01-04_16:47:09.840.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Vaishnavi Ravikumar |
| SpeciesList | scientific name: Bicyclus anynana; NCBI TaxID: NEWT:110368; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-06-27 07:41:32 | ID requested | |
| ⏵ 1 | 2026-01-04 16:47:10 | announced | |
Publication List
| 10.3390/proteomes13040068; |
| Hesketh A, Kadiwala J, Ravikumar V, Garizo AR, Beldade P, Fournier M, Shakur R, A Proteomic View of Butterfly Metamorphosis. Proteomes, 13(4):(2025) [pubmed] |
Keyword List
| submitter keyword: whole proteome,Butterfly, metamorphosis |
Contact List
| Marjorie Fournier |
|---|
| contact affiliation | University of Oxford, Department of Biochemistry South Parks Road, Oxford, OX13QU |
| contact email | marjorie.fournier@bioch.ox.ac.uk |
| lab head | |
| Vaishnavi Ravikumar |
|---|
| contact affiliation | Dept. of Biochemistry, University of Oxford |
| contact email | vaishnavi.ravikumar@gmail.com |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/01/PXD065563 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD065563
- Label: PRIDE project
- Name: A proteomic view of butterfly morphogenesis
