PXD065543-1

PXD065543 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	GFP-PHF23 interactome in HeLa nuclear lysate
Description	PHF23 is a methyl reading protein with its PHD domain. We found PHF23 represses autophagy performed purification and identification of PHF23 interactome.
HostingRepository	PRIDE
AnnounceDate	2025-12-15
AnnouncementXML	Submission_2025-12-14_16:08:18.793.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Seon Ah Choi
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Exploris 240

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-06-26 22:19:37	ID requested
⏵ 1	2025-12-14 16:08:20	announced

Publication List

10.1093/nar/gkaf1317;
Choi SA, Kim J, Yu YS, Kim J, Kim SI, Bae H, Kwon J, Kim KI, Baek SH, Dual mechanism of autophagy gene repression by PHF23 and therapeutic potential of its inhibition in protein aggregation disorders. Nucleic Acids Res, 53(22):(2025) [pubmed]

10.1093/nar/gkaf1317;

Choi SA, Kim J, Yu YS, Kim J, Kim SI, Bae H, Kwon J, Kim KI, Baek SH, Dual mechanism of autophagy gene repression by PHF23 and therapeutic potential of its inhibition in protein aggregation disorders. Nucleic Acids Res, 53(22):(2025) [pubmed]

Keyword List

submitter keyword: PHF23, HeLa, nuclear interactome

submitter keyword: PHF23, HeLa, nuclear interactome

Contact List

Sung Hee Baek
contact affiliation	Creative Research Initiatives Center for Epigenetic Code and Diseases, School of Biological Sciences, Seoul National University, Seoul 08826, South Korea
contact email	sbaek@snu.ac.kr
lab head
Seon Ah Choi
contact affiliation	Seoul National University
contact email	seonachoi1@gmail.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/12/PXD065543
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/12/PXD065543

PRIDE project URI

Repository Record List

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