PXD065511-1

PXD065511 is an original dataset announced via ProteomeXchange.

Title	Proteomic analysis of surface proteins from C1s siRNA-treated UT-SCC-59A squamous cell carcinoma cells
Description	To investigate the effect of C1s on cell surface proteins cSCC cell cultures were transfected with 120 nM control or C1s siRNAs and after 3 days incubation, the cells were biotinylated collected by streptavidin beads and subsequently analyzed by LC-MS/MS.
HostingRepository	PRIDE
AnnounceDate	2026-03-03
AnnouncementXML	Submission_2026-03-03_04:13:24.173.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Pekka Rappu
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2025-06-26 06:02:13	ID requested
⏵ 1	2026-03-03 04:13:24	announced

10.1038/S41389-026-00606-4;

submitter keyword: squamous cell cancer, complement, C1s, biotinylation

Veli-Matti Kähäri
contact affiliation	Department of Dermatology, University of Turku, Turku, Finland
contact email	veli-matti.kahari@utu.fi
lab head
Pekka Rappu
contact affiliation	University of Turku
contact email	pekka.rappu@utu.fi
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/03/PXD065511

PRIDE project URI

• PRIDE
  1. PXD065511
     1. Label: PRIDE project
     2. Name: Proteomic analysis of surface proteins from C1s siRNA-treated UT-SCC-59A squamous cell carcinoma cells