PXD065503 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | SILAC E3 ligase activity-based profiling of interferon-stimulated THP-1 cells |
| Description | Activity-based probes that covalently label proteins with transthiolating E3 ligase activity were used to determine differential changes in E3 ligase activity upon interferon stimulation of monocytic THP-1 cells. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-05-22 |
| AnnouncementXML | Submission_2026-05-22_10:40:50.631.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Satpal Virdee |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | monohydroxylated residue; iodoacetamide derivatized residue |
| Instrument | LTQ Orbitrap Velos |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-06-26 04:55:23 | ID requested | |
| ⏵ 1 | 2026-05-22 10:40:51 | announced | |
Publication List
| Squair DR, Rivers E, Sowar H, Balci A, Harmo R, Wright DJ, Beniwal G, Soetens M, Mathur S, Tollervey A, Wood NT, Pao KC, Stanton C, Fletcher AJ, Virdee S, ZNFX1 uses two-component ubiquitin circuitry to quarantine viral RNA. Mol Cell, 86(6):1164-1181.e12(2026) [pubmed] |
| 10.1016/j.molcel.2026.02.015; |
Keyword List
| submitter keyword: SILAC, Activity-based probes |
Contact List
| Satpal Virdee |
|---|
| contact affiliation | MRC Protein phosphorylation and ubiquitylation unit, University of Dundee |
| contact email | s.s.virdee@dundee.ac.uk |
| lab head | |
| Satpal Virdee |
|---|
| contact affiliation | University of Dundee |
| contact email | s.s.virdee@dundee.ac.uk |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/05/PXD065503 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD065503
- Label: PRIDE project
- Name: SILAC E3 ligase activity-based profiling of interferon-stimulated THP-1 cells
