PXD065431-1

PXD065431 is an original dataset announced via ProteomeXchange.

Title	Light chain amyloid fibrils from an AL amyloidosis patient (case 2), abdominal fat biopsy
Description	In this study, we successfully extracted and resolved the high-resolution structure of amyloid fibrils from abdominal fat biopsy sample obtained from a living AL patient using cryo-EM.
HostingRepository	PRIDE
AnnounceDate	2025-12-23
AnnouncementXML	Submission_2025-12-22_21:44:07.845.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yuxuan Yao
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Exploris 480

Revision	Datetime	Status	ChangeLog Entry
0	2025-06-25 03:27:49	ID requested
⏵ 1	2025-12-22 21:44:08	announced

10.1073/PNAS.2515454123;

submitter keyword: None

Dan Li
contact affiliation	Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, China
contact email	yaoyuxuan@sjtu.edu.cn
lab head
Yuxuan Yao
contact affiliation	Shanghai Jiao Tong University
contact email	yaoyuxuan@sjtu.edu.cn
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/12/PXD065431

PRIDE project URI

• PRIDE
  1. PXD065431
     1. Label: PRIDE project
     2. Name: Light chain amyloid fibrils from an AL amyloidosis patient (case 2), abdominal fat biopsy