⮝ Full datasets listing
PXD065413-1
PXD065413 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Bacteria covalently incorporate polyfluoroalkyl carboxylates into membrane lipids |
| Description | Per- and polyfluoroalkyl substances (PFASs) are global contaminants of concern to human and environmental health 1. Little is known about biological attenuation processes and microbiota PFAS interactions. Here we show that the soil bacterium Pseudomonas sp. strain 273 covalently incorporates polyfluoroalkyl carboxylates (FTCAs) including 8:3 FTCA into phosphatidylethanolamine (PE) and phosphatidylglycerol (PG), two prominent components of lipid bilayers. Semi-quantitative lipidomic analysis estimated that 7.5% of the bacteriums phospholipid pool contained 8:3 FTCA, resulting in a PFAS membrane incorporation factor (MIF) of 423. Synthesis of PE and PG species carrying a polyfluorocarbon acyl tail was observed in five other axenic bacterial cultures tested, albeit with lower MIFs. Our results suggest that the formation of fluoromembranes is a prevalent bacterial process potentially impacting the fate, longevity, bioaccumulation, and biomagnification of certain PFASs. |
| HostingRepository | MassIVE |
| AnnounceDate | 2026-01-07 |
| AnnouncementXML | Submission_2026-01-07_08:07:19.045.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Non peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Dana Carper |
| SpeciesList | scientific name: Pseudomonas sp. 273; NCBI TaxID: 75692; |
| ModificationList | Carbamidomethyl; Oxidation |
| Instrument | Q Exactive Plus |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2025-06-24 17:43:53 | ID requested | |
| ⏵ 1 | 2026-01-07 08:07:19 | announced |
Publication List
| no publication |
Keyword List
| submitter keyword: PFASs, polyfluoroalkyl carboxylates, fluoromembranes, DatasetType:Proteomics |
Contact List
| Paul Abraham | |
|---|---|
| contact affiliation | ORNL |
| contact email | pav@ornl.gov |
| lab head | |
| Dana Carper | |
| contact affiliation | Oak Ridge National Laboratory |
| contact email | carperdl@ornl.gov |
| dataset submitter | |
Full Dataset Link List
| MassIVE dataset URI |
| Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive-ftp.ucsd.edu/v10/MSV000098309/ |
