PXD065308-1
PXD065308 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Immunotherapy has revolutionized cancer treatment and the management of autoimmune diseases |
| Description | Immunotherapy has revolutionized cancer treatment and the management of autoimmune diseases by harnessing the body's immune system. Checkpoint inhibitors, CAR-T cell therapy, and cancer vaccines have shown remarkable success, particularly in melanoma, hematologic malignancies, and some solid tumors. However, challenges remain, including variable patient responses, immune-related adverse events, and resistance mechanisms. Future research aims to enhance efficacy through combination therapies (e.g., with targeted agents or radiotherapy), novel biomarkers for patient stratification, and next-generation engineered immune cells (e.g., dual-targeting CAR-T, NK cell therapies). Additionally, advances in microbiome modulation, personalized neoantigen vaccines, and AI-driven drug design hold promise. Beyond oncology, immunotherapy is being explored for neurodegenerative, infectious, and inflammatory diseases. Overcoming toxicity, improving tumor microenvironment targeting, and expanding accessibility will be critical for the next decade of progress. |
| HostingRepository | iProX |
| AnnounceDate | 2025-06-23 |
| AnnouncementXML | Submission_2025-06-23_00:20:59.945.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Haohao Tang |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive HF-X; timsTOF Pro |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2025-06-23 00:20:00 | ID requested | |
| ⏵ 1 | 2025-06-23 00:21:00 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Immunotherapy,cancer treatment,autoimmune diseases |
Contact List
| Yang Chen | |
|---|---|
| contact affiliation | Peking University Health Science Center |
| contact email | chenyang1816185048@bjmu.edu.cn |
| lab head | |
| Haohao Tang | |
| contact affiliation | Peking University Health Science Center |
| contact email | Tanghaohao0987@163.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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