PXD065307-1

PXD065307 is an original dataset announced via ProteomeXchange.

Title	Proteomic Analysis of Human Nucleus Pulposus in Young and Elderly Individuals Using TMT Quantification
Description	This project investigates the differential proteomic profiles of human nucleus pulposus samples from young and elderly individuals. Using Tandem Mass Tag (TMT) quantification, we aim to identify and compare protein expression differences between the two groups. The research explores the biological implications of these differences, with a focus on understanding age-related changes at the molecular level in the nucleus pulposus, a key component of the intervertebral disc.
HostingRepository	iProX
AnnounceDate	2025-06-23
AnnouncementXML	Submission_2025-07-17_01:20:07.044.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Tianle Zhou
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Exploris 480

Revision	Datetime	Status	ChangeLog Entry
0	2025-06-23 00:18:01	ID requested
⏵ 1	2025-07-17 01:20:08	announced

Zhou T, Zhang T, He Q, Zhang Z, Huang Y, Chen Z, Wang W, B pathway activation in a multiomic study. Sci Rep, 15(1):25307(2025) [pubmed]

submitter keyword: Proteomics, Nucleus Pulposus, TMT Quantification, Young vs Elderly, Differential Proteins, Mass Spectrometry, Aging, Protein Expression, Human Samples

Wei Wang
contact affiliation	Hubei Provincial Hospital of Traditional Chinese Medicine
contact email	hbzyww@163.com
lab head
Tianle Zhou
contact affiliation	Hubei University of Chinese Medicine
contact email	1045551953@qq.com
dataset submitter

iProX dataset URI