PXD065304-1
PXD065304 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | The mechanism of lenvatinib resistance in HCC |
| Description | To investigate the mechanisms of lenvatinib resistance in HCC, we developed a lenvatinib-resistant cell lines,MHCC97H-R (97H-R), by incubating them with 5 μM lenvatinib in 6-well plates. The concentration was subsequently increased by 2.5 μM each week. These cells will be injected subcutaneously into nude mice and continued to be administered lenvatinib through in vivo administration. Harvest when it is determined that lenvatinib resistance has emerged. These cell will ejcted We conducted proteomic sequencing analyses of a lenvatinib-resistant cell line and wild cell line, identifying critical factors associated with lenvatinib resistance in HCC. |
| HostingRepository | iProX |
| AnnounceDate | 2025-06-23 |
| AnnouncementXML | Submission_2025-06-22_23:13:31.540.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Bugang Liang |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2025-06-22 23:13:07 | ID requested | |
| ⏵ 1 | 2025-06-22 23:13:31 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Human, lenvatinib resistant, HCC, LS-MSMS |
Contact List
| Aiwu Ke | |
|---|---|
| contact affiliation | Zhongshan Hospital |
| contact email | 23211210055@m.fudan.edu.cn |
| lab head | |
| Bugang Liang | |
| contact affiliation | Zhongshan Hospital |
| contact email | 907529280@qq.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
to receive all new ProteomeXchange dataset release announcements!
