PXD065189-1
PXD065189 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Rictor Regulates Global Phosphorylation Dynamics in Renal Cancer Cells in Response to Irradiation |
| Description | The mechanistic target of rapamycin complex 2 (mTORC2) plays a critical role in tumor biology; however, its biological function in DNA damage repair remains poorly understood. To investigate its role, we established renal cancer cell lines with stable knockdown of Rictor, a core component of mTORC2, and subjected them to ionizing radiation. Subsequently, we performed a global phosphoproteomic analysis to profile phosphorylation events regulated by Rictor under radiation-induced stress. |
| HostingRepository | iProX |
| AnnounceDate | 2025-06-19 |
| AnnouncementXML | Submission_2025-06-18_20:33:50.486.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Hao Wang |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | phosphorylated residue |
| Instrument | Orbitrap Fusion Lumos |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2025-06-18 20:33:29 | ID requested | |
| ⏵ 1 | 2025-06-18 20:33:50 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Rictor,Renal Cancer,ACHN,Phospho-proteomics |
Contact List
| Ruibing Chen | |
|---|---|
| contact affiliation | Tianjin University |
| contact email | rbchen@tju.edu.cn |
| lab head | |
| Hao Wang | |
| contact affiliation | Henan Cancer Hospital |
| contact email | wanghao123@tmu.edu.cn |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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