PXD065136 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Ubiquitinomic data: Evolutionarily conserved E3 ubiquitin ligase modulates carotenoid, sterol and lipid crosstalk |
| Description | After disrupting the E3 ligase PTR1 in Xanthophyllomyces dendrorhous CBS 6938 (Xd-ptr1), we observed a quadrupling of astaxanthin production, accompanied by increased levels of ergosterol and stellasterol. This disruption also resulted in a reduction of total lipids, a shift in fatty acid composition toward polyunsaturated species, and a decrease in triglyceride levels. To elucidate the mechanism by which PTR1 regulates carotenoid, sterol, and lipid metabolism, we conducted a ubiquitinomic analyse. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-04-09 |
| AnnouncementXML | Submission_2026-04-09_06:59:47.583.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Ruilin Huang |
| SpeciesList | scientific name: Phaffia rhodozyma; NCBI TaxID: NEWT:264483; |
| ModificationList | ubiquitination signature dipeptidyl lysine; monohydroxylated residue; iodoacetamide derivatized residue |
| Instrument | Q Exactive HF-X |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-06-17 20:48:48 | ID requested | |
| ⏵ 1 | 2026-04-09 06:59:48 | announced | |
Publication List
Keyword List
| submitter keyword: E3 ubiquitin ligase, Xanthophyllomyces dendrorhous |
Contact List
| Shi'an Wang |
|---|
| contact affiliation | 1. Key Laboratory of Photoelectric Conversion and Utilization of Solar Energy, Shandong Provincial Key Laboratory of Synthetic Biology, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, 266101, China. 2. Shandong Energy Institute, Qingdao 266101, China. 3. Qingdao New Energy Shandong Laboratory, Qingdao 266101, China. |
| contact email | wangsa@qibebt.ac.cn |
| lab head | |
| Ruilin Huang |
|---|
| contact affiliation | Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences |
| contact email | huangrl@qibebt.ac.cn |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
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| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD065136
- Label: PRIDE project
- Name: Ubiquitinomic data: Evolutionarily conserved E3 ubiquitin ligase modulates carotenoid, sterol and lipid crosstalk
