PXD065125-1

PXD065125 is an original dataset announced via ProteomeXchange.

Title	The Parkinson’s disease kinase LRRK2 impairs release sites of vulnerable dopamine axons
Description	Data relating to the section: "Phosphorylation of Rab3a decreases its binding to the effector proteins Rim1&2 from mouse brain". The data of this submission is part of a larger screen of Rab/pRab interactors, and therefore, DIA-NN search output files contain additional sample columns that remain blinded.
HostingRepository	PRIDE
AnnounceDate	2026-05-27
AnnouncementXML	Submission_2026-05-27_03:56:12.020.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Matthew Jaconelli
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090;
ModificationList	iodoacetamide derivatized residue
Instrument	Orbitrap Astral

Revision	Datetime	Status	ChangeLog Entry
0	2025-06-17 11:43:10	ID requested
⏵ 1	2026-05-27 03:56:12	announced

Dataset with its publication pending

submitter keyword: Rab3a, LRRK2, dopamine neurons, phosphorylation

Prof. Dario R. Alessi
contact affiliation	Science Director MRC PPU, School of Life Sciences, University of Dundee, UK.
contact email	d.r.alessi@dundee.ac.uk
lab head
Matthew Jaconelli
contact affiliation	University of Dundee
contact email	mjaconelli001@dundee.ac.uk
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/05/PXD065125

PRIDE project URI

• PRIDE
  1. PXD065125
     1. Label: PRIDE project
     2. Name: The Parkinson’s disease kinase LRRK2 impairs release sites of vulnerable dopamine axons