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PXD065027-1

PXD065027 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleAP-MS Screening for novel Ribosome Biogenesis factors revealing 55LCC
DescriptionData from our initital screening for novel biogenesis factors in human ribosome biogenesis, revealing 55LCC interaction and interaction within 55LCC. Further, the dataset includes 55LCC depletion data trapping the pre-60S, enriching non-released biogenesis factors on the pre-60S. In addition transgene variants were tested and the dependency of SPATA5L1 ATPase activity for Ribosome-55LCC interaction via GTPBP4-FLAG silac interactome in the presence of dual ATPase dead mutant while endogen was depleted.
HostingRepositoryPRIDE
AnnounceDate2026-07-29
AnnouncementXMLSubmission_2026-07-29_12:37:56.921.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterJonas Walter
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationListNo PTMs are included in the dataset
InstrumentOrbitrap Exploris 480; Q Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-06-15 06:06:19ID requested
12026-07-29 12:37:57announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Human, AP-MS, Ribosome, 55LCC
Contact List
Chunaram Choudhary
contact affiliationUniversity of Copenhagen, Novo Nordisk Center for Protein Research, Proteomics Department, Proteomics and Cell Signaling Lab
contact emailchuna.choudhary@cpr.ku.dk
lab head
Jonas Walter
contact affiliationUniversity of Bonn
contact emailjonaswalter@posteo.de
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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