PXD064916 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Lysine acetylomic profiling of hybrid rice HY73 in response to drought |
| Description | This study investigates the molecular mechanisms underlying drought-resistant heterosis (DRH) in the elite hybrid rice HY73. Utilizing a quantitative lysine acetylome profiling approach on flag leaves of HY73 under well-watered (WW) and drought-stressed (DS) conditions, we aimed to unravel the role of protein lysine acetylation (Kac) in carbon metabolic reprogramming during drought adaptation. Critically, we identified phosphoglucomutase (OsPGM3) as a key metabolic switch whose K155 acetylation (K155ac) is dynamically downregulated under DS. This regulation orchestrates a strategic carbon reallocation, optimizing glucose-6-phosphate (G6P) flux towards lipid biosynthesis for stress resilience (MOS-AcCoA-FA/PR pathway) while maintaining efficient glucose-1-phosphate (G1P)-mediated sucrose export for yield potential. This dataset provides valuable insights into the sophisticated post-translational regulatory network that underpins superior DRH and yield stability in hybrid rice under water scarcity. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-06-28 |
| AnnouncementXML | Submission_2026-06-28_00:57:40.609.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Wenbo Cheng |
| SpeciesList | scientific name: Oryza sativa (Rice); NCBI TaxID: NEWT:4530; |
| ModificationList | acetylated residue |
| Instrument | Orbitrap Exploris 480 |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-06-11 23:03:52 | ID requested | |
| ⏵ 1 | 2026-06-28 00:57:41 | announced | |
Publication List
| Ding W, Bi J, Chen S, Wu Z, Liao Z, Huang L, Luo L, Chen L, Zhang X, Integrated multi-omics analysis reveals carbon metabolic reprogramming as a mechanism of drought resistance in hybrid rice. Plant Commun, ():101936(2026) [pubmed] |
| 10.1016/j.xplc.2026.101936; |
Keyword List
| submitter keyword: Hybrid rice, Drought resistance, Lysine acetylation, Acetylome, Heterosis |
Contact List
| Wei Ding |
|---|
| contact affiliation | State Key Laboratory of Genetic Engineering, Department of Biochemistry and Biophysics, School of Life Sciences, Fudan University, Shanghai, 200438, China. |
| contact email | dingw21@m.fudan.edu.cn |
| lab head | |
| Wenbo Cheng |
|---|
| contact affiliation | Shanghai Omicsspace Bioteh CO., LTD |
| contact email | wbcheng@omicsspace.com |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/06/PXD064916 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD064916
- Label: PRIDE project
- Name: Lysine acetylomic profiling of hybrid rice HY73 in response to drought
