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PXD064914-1

PXD064914 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProfiling proteins with altered structures in senescent cells through limited-proteolysis mass spectrometry (LiP-MS).
DescriptionAfter inducing LO2 cells to undergo senescence, the cells were grinded and homogenized, and then divided into two equal portions. One group was subjected to enzymatic cleavage using trypsin, while the other group was first treated with proteinase K and subsequently with trypsin. Both groups underwent protein identification through a Data-Independent Acquisition (DIA) mode.
HostingRepositoryiProX
AnnounceDate2025-06-12
AnnouncementXMLSubmission_2026-01-04_00:41:00.554.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterTianxiang Wang
SpeciesList scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentOrbitrap Astral
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-06-11 22:55:42ID requested
12026-01-04 00:41:01announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: protein structural changes, senescent cells, lip-ms
Contact List
Haiteng Deng
contact affiliationTsinghua University
contact emaildht@mail.tsinghua.edu.cn
lab head
Tianxiang Wang
contact affiliationTsinghua University
contact emailwtx20@mails.tsinghua.edu.cn
dataset submitter
Full Dataset Link List
iProX dataset URI