PXD064831-1

PXD064831 is an original dataset announced via ProteomeXchange.

Title	Interactome of DPYSL5 protein in H4 cells
Description	Here, using interactome analysis of DPYSL5 protein expressed in H4 cells, we provide a data-rich resource that reveals novel molecular insights into how DPYSL5 interact with associated proteins. Furthermore, by analyzing mutant forms of DPYSL5 identified in patients, we offer insights into how these mutations confer pathogenicity.
HostingRepository	PRIDE
AnnounceDate	2026-05-05
AnnouncementXML	Submission_2026-05-05_07:00:04.743.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Kohji Kato
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationList	No PTMs are included in the dataset
Instrument	Proteome Discoverer; Orbitrap Fusion; Xcalibur

Revision	Datetime	Status	ChangeLog Entry
0	2025-06-10 06:31:54	ID requested
⏵ 1	2026-05-05 07:00:05	announced

10.1126/SCITRANSLMED.ADT2426;

submitter keyword: Interactome,H4, TMT label, DPYSL5, LC-MS/MS

Peter J. Cullen
contact affiliation	School of Biochemistry, Faculty of Life Sciences, University of Bristol,UK
contact email	pete.cullen@bristol.ac.uk
lab head
Kohji Kato
contact affiliation	University of Bristol
contact email	kohji.kato@bristol.ac.uk
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/05/PXD064831

PRIDE project URI

• PRIDE
  1. PXD064831
     1. Label: PRIDE project
     2. Name: Interactome of DPYSL5 protein in H4 cells