PXD064747-1

PXD064747 is an original dataset announced via ProteomeXchange.

Title	Proteomics analysis of lipid-induced granules
Description	During the processes of MAFLD and MASH, DDX49 undergoes liquid-liquid phase separation. Subsequently, we used OA/PA (2:1) to simulate the MASH model in vitro. After treating HHL5 cells with OA/PA for 24 hours, we separated the lipid-organized particles of DDX49 by differential centrifugation. To investigate the composition of these particles and study their functions, we conducted a 10-fold proteomic analysis.
HostingRepository	PRIDE
AnnounceDate	2026-01-09
AnnouncementXML	Submission_2026-01-09_08:29:15.912.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yunhui Li
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationList	No PTMs are included in the dataset
Instrument	timsTOF HT

Revision	Datetime	Status	ChangeLog Entry
0	2025-06-08 07:38:46	ID requested
⏵ 1	2026-01-09 08:29:16	announced

10.1016/J.CMET.2025.12.015;

submitter keyword: proteomics

Yunhui Li
contact affiliation	National Key Laboratory of Immunity and Inflammation, Naval Medical University, Shanghai 200433, China
contact email	liyunhuigirl@163.com
lab head
Yunhui Li
contact affiliation	National Key Laboratory of Immunity and Inflammation
contact email	liyunhuigirl@163.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/01/PXD064747

PRIDE project URI

• PRIDE
  1. PXD064747
     1. Label: PRIDE project
     2. Name: Proteomics analysis of lipid-induced granules