PXD064605-1

PXD064605 is an original dataset announced via ProteomeXchange.

Title	TMT-based quantitative proteomic profiling of brain tissue from multiparous and nulliparous 5xFAD mice
Description	TMT-based quantitative proteomic profiling of brain tissue from multiparous and nulliparous 5xFAD mice
HostingRepository	PRIDE
AnnounceDate	2026-06-08
AnnouncementXML	Submission_2026-06-07_16:13:31.347.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yang Renzhi
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090;
ModificationList	TMT6plex-126 reporter+balance reagent acylated residue
Instrument	LTQ Orbitrap Velos

Revision	Datetime	Status	ChangeLog Entry
0	2025-06-03 23:56:14	ID requested
⏵ 1	2026-06-07 16:13:32	announced

Yang R, He Y, Pan Y, Geng A, Huang F, Guo K, Zhang H, accumulation and promotes cellular senescence in a mouse model of amyloidosis. Immun Ageing, 23(1):(2026) [pubmed]

10.1186/s12979-026-00565-9;

submitter keyword: multiparity,alzheimer's disease, brain, TMT,female 5xFAD mouse, LC-MS/MS

Hongsheng Zhang
contact affiliation	Chongqing Medical University
contact email	103115@cqmu.edu.cn
lab head
Yang Renzhi
contact affiliation	chongqing medical university
contact email	yang.renzhi.0805@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/06/PXD064605

PRIDE project URI

• PRIDE
  1. PXD064605
     1. Label: PRIDE project
     2. Name: TMT-based quantitative proteomic profiling of brain tissue from multiparous and nulliparous 5xFAD mice