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PXD064585-1

PXD064585 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleRSK Inhibition Rewires Kinase Networks in Esophageal Cancer (proteomics)
DescriptionOur study reveals that RSK inhibition reprograms kinase networks to enforce stress adaptation, maintaining oncogenic homeostasis despite perturbations. These findings highlight a potential therapeutic window for early intervention strategies, suggesting that combination strategies may enhance the efficacy of RSK-directed therapies in ESCC.
HostingRepositoryiProX
AnnounceDate2025-06-03
AnnouncementXMLSubmission_2025-06-03_19:40:18.262.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterXi Chen
SpeciesList scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentOrbitrap Astral
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-06-03 19:39:51ID requested
⏵ 12025-06-03 19:40:18announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: RSK inhibitor, ESCC, proteomics
Contact List
Xi Chen
contact affiliationSichuan Provincial People’s Hospital
contact emailcxde515@uestc.edu.cn
lab head
Xi Chen
contact affiliationSichuan Provincial People’s Hospital
contact emailcxde515@uestc.edu.cn
dataset submitter
Full Dataset Link List
iProX dataset URI

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