PXD064519-1

PXD064519 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Hippocampal proteome in human model of Temporal Lobe Epilepsy
Description	To scrutinize the proteomic changes that occur in human temporal lobe epilepsy, we compare peptides present in tissue from sclerotic and non-sclerotic temporal lobe epilepsy resected hippocampi and from non-epilepsy autopsy control tissue
HostingRepository	PRIDE
AnnounceDate	2025-07-28
AnnouncementXML	Submission_2025-07-27_16:15:52.659.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Marc-Michel Wilson
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-06-02 09:26:35	ID requested
⏵ 1	2025-07-27 16:15:54	announced

Publication List

10.1172/jci.insight.188612;
Mathoux J, Wilson MM, Srinivas S, Litovskich G, Villalba Benito L, Tran C, Kesavan J, Harnett A, Auer T, Sanz-Rodriguez A, Kh A E Alkhayyat M, Sullivan M, Liu Z, Huang Y, Lacey A, Delanty N, Cryan J, Brett FM, Farrell MA, O'Brien DF, Casillas-Espinosa PM, Jimenez-Mateos EM, Glennon JC, Canavan M, Henshall DC, Brennan GP, N6-methyladenosine (m6A) dysregulation contributes to network excitability in temporal lobe epilepsy. JCI Insight, 10(14):(2025) [pubmed]

10.1172/jci.insight.188612;

Mathoux J, Wilson MM, Srinivas S, Litovskich G, Villalba Benito L, Tran C, Kesavan J, Harnett A, Auer T, Sanz-Rodriguez A, Kh A E Alkhayyat M, Sullivan M, Liu Z, Huang Y, Lacey A, Delanty N, Cryan J, Brett FM, Farrell MA, O'Brien DF, Casillas-Espinosa PM, Jimenez-Mateos EM, Glennon JC, Canavan M, Henshall DC, Brennan GP, N6-methyladenosine (m6A) dysregulation contributes to network excitability in temporal lobe epilepsy. JCI Insight, 10(14):(2025) [pubmed]

Keyword List

submitter keyword: Human, MS/MS, TLE, Temporal lobe epilepsy

submitter keyword: Human, MS/MS, TLE, Temporal lobe epilepsy

Contact List

Gary, P, Brennan
contact affiliation	UCD School of Biomolecular and Biomedical Science, University College Dublin, Belfield, Dublin 4, Ireland
contact email	gary.brennan@ucd.ie
lab head
Marc-Michel Wilson
contact affiliation	UCD Clinical Research Centre, School of Medicine, University College Dublin, Dublin, Ireland
contact email	marc.wilson@ucd.ie
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/07/PXD064519
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/07/PXD064519

PRIDE project URI

Repository Record List

[ + ]