PXD064426 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Human N-terminal proteome using TMPP labelling and dN-TOP approach |
| Description | The present study describes the free N-terminome analysis of human mitochondria-enriched samples using trimethoxyphenylphosphonium (TMPP) labelling approaches and dN-TOP validation of the proteomics data acquired with an Orbitrap mass spectrometer. The doublet N-terminal oriented proteomics (dN-TOP) strategy is based on a double light/heavy TMPP labelling which enable fast, efficient and reliable high throughput N-terminome data validation |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-03-23 |
| AnnouncementXML | Submission_2026-03-22_17:44:18.485.xml |
| DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD064426 |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Supported dataset by repository |
| PrimarySubmitter | Magali Rompais |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | monohydroxylated residue; iodoacetamide derivatized residue |
| Instrument | Q Exactive Plus |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
| 0 | 2025-05-29 12:56:15 | ID requested | |
| ⏵ 1 | 2026-03-22 17:44:19 | announced | |
Publication List
| 10.1038/s41467-026-68981-5; |
| 10.6019/PXD064426; |
| Bouwmeester R, Nameni A, Declercq A, Devreese R, Velghe K, Gorshkov V, Penanes PA, Kjeldsen F, Rompais M, Carapito C, Gabriels R, Martens L, Transfer learning in DeepLC improves LC retention time prediction across substantially different modifications and setups. Nat Commun, 17(1):(2026) [pubmed] |
Keyword List
| submitter keyword: dN-TOP approach,Free N-Terminome analysis, Human mitochondria |
Contact List
| Christine CARAPITO |
| contact affiliation | LSMBO, DSA, IPHC-UMR7178, CNRS, Université de Strasbourg |
| contact email | ccarapito@unistra.fr |
| lab head | |
| Magali Rompais |
| contact affiliation | IPHC-UMR7178-CNRS-UDS-LSMBO |
| contact email | magali.rompais@unistra.fr |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
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| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD064426
- Label: PRIDE project
- Name: Human N-terminal proteome using TMPP labelling and dN-TOP approach