PXD064307-1

PXD064307 is an original dataset announced via ProteomeXchange.

Title	The function of PTRH2 at mitochondria
Description	The integrin effector, PTRH2, associates with mitochondria in adherent cells where its function has not been elucidated. PTRH2 loss-of-function mutations cause multisystem disease in children through an unknown mechanism. We sought to determine the role of mitochondrial PTRH2. We used IP/MS proteomics to identify PTRH2 interacting partners.
HostingRepository	PRIDE
AnnounceDate	2025-12-27
AnnouncementXML	Submission_2025-12-27_08:54:09.100.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD064307
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Jennifer Klein
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090;
ModificationList	acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion

Revision	Datetime	Status	ChangeLog Entry
0	2025-05-26 09:09:53	ID requested
⏵ 1	2025-12-27 08:54:09	announced

10.6019/PXD064307;

submitter keyword: metabolism,PTRH2, mitochondria, apoptosis, integrin

Michelle L. Matter
contact affiliation	Tulane University School of Medicine, Biochemistry and Molecular Biology New Orleans, LA 70112 USA
contact email	mmatter@tulane.edu
lab head
Jennifer Klein
contact affiliation	LSUHSC
contact email	jklei1@lsuhsc.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/12/PXD064307

PRIDE project URI

• PRIDE
  1. PXD064307
     1. Label: PRIDE project
     2. Name: The function of PTRH2 at mitochondria