PXD064284-1
PXD064284 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Act1 disrupts SHP2 stability by shifting the pyroglutamylation-ubiquitination balance to inhibit tumor progression |
| Description | SHP2 stability is regulated by the dynamic antagonism of pyroglutamylation and ubiquitination, with Act1 influencing this balance, impacting cancer progression and therapy. |
| HostingRepository | iProX |
| AnnounceDate | 2025-05-23 |
| AnnouncementXML | Submission_2025-05-25_22:27:58.892.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Xuejiao Liang |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | 5800 TOF/TOF |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2025-05-25 21:57:41 | ID requested | |
| ⏵ 1 | 2025-05-25 22:27:59 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: QPCTL, SHP2, pyroglutamylation |
Contact List
| Qiong Luo | |
|---|---|
| contact affiliation | Nanjing University |
| contact email | luoyiqing8@163.com |
| lab head | |
| Xuejiao Liang | |
| contact affiliation | Nanjing University |
| contact email | xuejiao_liang@126.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |




