PXD064241-1

PXD064241 is an original dataset announced via ProteomeXchange.

Title	The structure and composition of native human nucleosomes
Description	In this study, we analysed the composition of histone modifications on native nucleosomes purified from HEK293 cells.
HostingRepository	PRIDE
AnnounceDate	2026-01-12
AnnouncementXML	Submission_2026-01-11_16:37:14.298.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Jason Low
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationList	propanoylated residue
Instrument	Q Exactive HF-X

Revision	Datetime	Status	ChangeLog Entry
0	2025-05-23 07:27:41	ID requested
⏵ 1	2026-01-11 16:37:15	announced

10.1093/nar/gkaf1406;

Lambrechts LS, Reid XJ, Kambanis L, Luong C, Kobakhidze E, Daners A, Zhong Y, Patel K, Franck CK, Sani HM, Taylor C, Low JKK, Payne RJ, Mackay JP, The BRD4-nucleosome interaction is enhanced modestly and non-selectively by histone acetylation. Nucleic Acids Res, 53(22):(2025) [pubmed]

submitter keyword: PTMs, CryoEM,Nucleosomes, Histones

Joel Mackay
contact affiliation	School of Life and Environmental Sciences, University of Sydney, NSW 2006 Australia
contact email	joel.mackay@sydney.edu.au
lab head
Jason Low
contact affiliation	The University of Sydney
contact email	jason.low@sydney.edu.au
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/01/PXD064241

PRIDE project URI

• PRIDE
  1. PXD064241
     1. Label: PRIDE project
     2. Name: The structure and composition of native human nucleosomes