PXD063915-1

PXD063915 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Analysis of the protein corona on nanoparticles in mouse plasma
Description	We designed three types of nanoparticles with different lipid compositions, each exhibiting distinct tumor accumulation efficiencies. By isolating the protein corona formed on these nanoparticles in mouse plasma, we performed mass spectrometry to characterize the differential protein adsorption profiles. This analysis allowed us to identify key proteins potentially responsible for enhancing tumor accumulation of nanoparticles.
HostingRepository	PRIDE
AnnounceDate	2025-07-21
AnnouncementXML	Submission_2025-07-20_16:09:28.956.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	qikai wang
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-05-14 00:22:39	ID requested
⏵ 1	2025-07-20 16:09:29	announced

Publication List

Liu Y, Wang Q, Feng Z, Qin M, Zhang Z, Jiang J, Ren T, Liu X, Jeffrey Brinker C, Zhao Y, Meng H, Unlocking tumor barrier: annexin A2-mediated transcytosis boosts drug delivery in pancreatic and breast tumors. Nat Commun, 16(1):6531(2025) [pubmed]
10.1038/s41467-025-61434-5;

Liu Y, Wang Q, Feng Z, Qin M, Zhang Z, Jiang J, Ren T, Liu X, Jeffrey Brinker C, Zhao Y, Meng H, Unlocking tumor barrier: annexin A2-mediated transcytosis boosts drug delivery in pancreatic and breast tumors. Nat Commun, 16(1):6531(2025) [pubmed]

10.1038/s41467-025-61434-5;

Keyword List

submitter keyword: protein corona, nanoparticle

submitter keyword: protein corona, nanoparticle

Contact List

Huan Meng
contact affiliation	CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology, Beijing, China
contact email	mengh@nanoctr.cn
lab head
qikai wang
contact affiliation	National Center for Nanoscience and Technology
contact email	sevenk@126.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/07/PXD063915
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/07/PXD063915

PRIDE project URI

Repository Record List

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