PXD063853-1

PXD063853 is an original dataset announced via ProteomeXchange.

Title	4DSmartDIA protein quantification omics of two mouse IP elution samples (no duplication)
Description	Based on the Raw files obtained by mass spectrometry detection, 1) Construct a sample-specific protein database according to the source of the samples, and then conduct database search using analysis software; 2) Conduct quality control analysis at the peptide and protein levels based on the results of database search; 3) Conduct quantitative analysis of proteins, including quantitative distribution and repeatability analysis; 4) Perform common functional annotations on the identified proteins, including GO, KEGG, Protein domain, COG/KOG, STRING database annotations, etc. 6) Functional classification statistical analysis of proteins between the two groups was conducted, including GO secondary classification, subcellular localization classification, COG/KOG classification and KEGG pathway classification statistics; 7) The Fisher's exact test method was used to conduct enrichment analysis on the differentially expressed proteins between the two groups, involving the functions of GO, KEGG and Protein domain; 8) When the project has multiple experimental groups, the functional relationships of differentially expressed proteins under different experimental conditions are compared through rich cluster analysis. 9) Through Protein-protein interaction network (PPI) analysis, the key regulatory proteins under specific experimental conditions were screened out.
HostingRepository	PRIDE
AnnounceDate	2026-06-15
AnnouncementXML	Submission_2026-06-14_16:08:32.706.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Xinyue Li
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090;
ModificationList	No PTMs are included in the dataset
Instrument	timsTOF Pro 2

Revision	Datetime	Status	ChangeLog Entry
0	2025-05-12 05:47:08	ID requested
⏵ 1	2026-06-14 16:08:33	announced

10.1002/advs.202520059;

Li X, Hu X, Wu J, N4-acetylcytidine in LncRNA Gm26917 Promotes Translation in Female Germline Stem Cells by Recruiting Ribosomal Protein mRNA via EEF1A1. Adv Sci (Weinh), 13(30):e20059(2026) [pubmed]

submitter keyword: lc-ms,IP

Xinyue Li
contact affiliation	shanghai jiaotong university
contact email	1419974394@qq.com
lab head
Xinyue Li
contact affiliation	shanghai jiaotong university
contact email	1419974394@qq.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/06/PXD063853

PRIDE project URI

• PRIDE
  1. PXD063853
     1. Label: PRIDE project
     2. Name: 4DSmartDIA protein quantification omics of two mouse IP elution samples (no duplication)