PXD063772 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Bioengineering of the implantable vascularized endocrine constructs for insulin delivery suitable for clinical upscaling |
| Description | Beta cell replacement therapy for type 1 diabetes is hindered by poor graft survival and suboptimal function, largely due to inadequate vascularization and lack of supportive microenvironment. To address these challenges, we developed a clinically scalable, extracellular matrix (ECM)–mimetic hydrogel, termed Amniogel, derived from human amniotic membrane via streamlined, clinically compliant process. Co-encapsulation of pancreatic islets with blood outgrowth endothelial cells (BOECs) within Amniogel facilitated the formation of prevascularized endocrine constructs (VECs). |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-04-24 |
| AnnouncementXML | Submission_2026-04-24_09:23:03.663.xml |
| DigitalObjectIdentifier | https://doi.org/10.6019/PXD063772 |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Supported dataset by repository |
| PrimarySubmitter | Fanny Lebreton |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | monohydroxylated residue; deamidated residue |
| Instrument | Q Exactive |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-05-08 10:20:25 | ID requested | |
| ⏵ 1 | 2026-04-24 09:23:04 | announced | |
Publication List
Keyword List
| submitter keyword: Human, bioartificial pancreas |
Contact List
| Ekaterine Berishvili |
|---|
| contact affiliation | Laboratory of Tissue Engineering and Organ Regeneration, Department of Surgery, University of Geneva, Geneva, Switzerland |
| contact email | ekaterine.berishvili@unige.ch |
| lab head | |
| Fanny Lebreton |
|---|
| contact affiliation | Hopitaux Universitaires de Genève |
| contact email | fanny.lebreton@unige.ch |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/04/PXD063772 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD063772
- Label: PRIDE project
- Name: Bioengineering of the implantable vascularized endocrine constructs for insulin delivery suitable for clinical upscaling
