PXD063538-1

PXD063538 is an original dataset announced via ProteomeXchange.

Title	Phospho-Peptide Pull-Down Reveals Inhibitory Signaling Partners of CD200R1
Description	Project Description (Revised): CD200R1 inhibits phagocytosis through its intracellular tyrosine residues Y286 and Y297. To investigate whether these residues recruit inhibitory molecules, we performed pull-down assays using synthetic peptides—either phosphorylated or unphosphorylated—corresponding to regions containing Y286 and Y297. These peptides were incubated with lysates from mouse bone marrow-derived macrophages (BMDMs), and interacting proteins were subsequently identified by mass spectrometry.
HostingRepository	PRIDE
AnnounceDate	2025-09-17
AnnouncementXML	Submission_2025-09-17_08:18:46.083.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Jiaxin Li
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive; Orbitrap Fusion

Revision	Datetime	Status	ChangeLog Entry
0	2025-05-01 10:22:59	ID requested
⏵ 1	2025-09-17 08:18:46	announced

10.1038/S41467-025-60456-3;

ProteomeXchange project tag: Biology/Disease-Driven Human Proteome Project (B/D-HPP), Human Proteome Project

submitter keyword: phagocytosis,CD200R1, macrophages, BMDMs

Jiaxin Li and Andre Veillette
contact affiliation	Laboratory of Molecular Oncology1, Institut de recherches cliniques de Montréal (IRCM), Montréal, Québec, Canada H2W1R7; Department of Medicine2, McGill University, Montréal, Québec, Canada H3G 1Y6
contact email	jiaxin.li@mail.mcgill.ca
lab head
Jiaxin Li
contact affiliation	IRCM, McGill University
contact email	jiaxin.li@mail.mcgill.ca
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/09/PXD063538

PRIDE project URI

• PRIDE
  1. PXD063538
     1. Label: PRIDE project
     2. Name: Phospho-Peptide Pull-Down Reveals Inhibitory Signaling Partners of CD200R1