PXD063528-1

PXD063528 is an original dataset announced via ProteomeXchange.

Title	Induction of anti-tumour immunogenicity via modulation of nonsense-mediated decay
Description	This project explores the role of SMG1 on the Nonsense-mediated decay (NMD) pathway in two human cell lines – PC9 (lung) and A375 (epithelial). The conditions used were a DMSO control for two SMG1 inhibitors, and an siRNA control for the siSMG1 RNA knock-down condition.
HostingRepository	PRIDE
AnnounceDate	2026-04-07
AnnouncementXML	Submission_2026-04-07_11:27:46.761.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Silvia Surinova
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Exploris 480

Revision	Datetime	Status	ChangeLog Entry
0	2025-05-01 04:01:05	ID requested
⏵ 1	2026-04-07 11:27:47	announced

10.1016/J.IMMUNI.2026.02.005;

submitter keyword: Human, LC-MS/MS

Dr Silvia Surinova
contact affiliation	Team Lead in Proteomics Head of the Proteomics Research Translational Technology Platform UCL Cancer Institute 72 Huntley Street, London, WC1E 6DD, UK
contact email	s.surinova@ucl.ac.uk
lab head
Silvia Surinova
contact affiliation	UCL
contact email	s.surinova@ucl.ac.uk
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/04/PXD063528

PRIDE project URI

• PRIDE
  1. PXD063528
     1. Label: PRIDE project
     2. Name: Induction of anti-tumour immunogenicity via modulation of nonsense-mediated decay