PXD063320 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Proteomic analysis of gemcitabine-resistant (GemR) versus paired control human pancreatic cancer cells (PCCs) |
| Description | In search of potential markers of treatment response, comparative LC-MS/MS-based proteomic analysis of GemR and paired control PCCs was performed. It includes four different PCC lines including three primary - PCC-1 (c1), PCC-2 (c2), PCC-7 (c3) and Mia PaCa-2 (c4). Cells were maintained in DMEM supplemented with 10% FBS, with or without gemcitabine (50-150 nM) for upto 40 passages. Cell lysates in triplicate from GemR and paired control cells collected at six different passages (p10, p20, p25, p30, p35, and p40) during treatment period were analyzed using LC-MS/MS |
| HostingRepository | PRIDE |
| AnnounceDate | 2025-11-04 |
| AnnouncementXML | Submission_2025-11-04_12:33:15.283.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Ingrid Maria Erika Ekman Stensland |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | timsTOF Pro 2 |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-04-25 03:36:11 | ID requested | |
| ⏵ 1 | 2025-11-04 12:33:16 | announced | |
Publication List
| 10.3390/proteomes13040048; |
| Amrutkar M, Li Y, Finstadsveen AV, Verbeke CS, Gladhaug IP, Proteomic Characterization of Primary Human Pancreatic Cancer Cell Lines Following Long-Term Exposure to Gemcitabine. Proteomes, 13(4):(2025) [pubmed] |
Keyword List
| submitter keyword: proteome profiling,Pancreatic cancer, gemcitabine resistance, LC-MS/MS |
Contact List
| Tuula A. Nyman |
|---|
| contact affiliation | The Proteomics Core Facility (PCF) at Oslo University Hospital |
| contact email | t.a.nyman@medisin.uio.no |
| lab head | |
| Ingrid Maria Erika Ekman Stensland |
|---|
| contact affiliation | Oslo University hospital |
| contact email | maria.stensland@medisin.uio.no |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
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| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD063320
- Label: PRIDE project
- Name: Proteomic analysis of gemcitabine-resistant (GemR) versus paired control human pancreatic cancer cells (PCCs)
