PXD063194 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Treadmill training and venlafaxine treatment on brain changes induced by prenatal dexamethasone. |
| Description | Prenatal exposure to dexamethasone (DEX) is known to induce long-term behavioral and molecular impairments. This research investigated whether moderate physical exercise (treadmill running) and venlafaxine administration, or their combination, applied in early adulthood, could modulate the behavioral and brain molecular alterations induced by prenatal DEX exposure. It was demonstrated that both exercise and venlafaxine treatment ameliorated deficits in memory, depressive-like behavior, and anxiety-like behavior. Subsequent proteomic analysis of the frontal cortex revealed significant modulation in the proteome following each intervention. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-03-13 |
| AnnouncementXML | Submission_2026-03-13_12:41:30.022.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Maciej Suski |
| SpeciesList | scientific name: Rattus norvegicus (Rat); NCBI TaxID: NEWT:10116; |
| ModificationList | iodoacetamide derivatized residue |
| Instrument | Orbitrap Exploris 480 |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-04-22 06:53:28 | ID requested | |
| ⏵ 1 | 2026-03-13 12:41:30 | announced | |
Publication List
| 10.1016/j.neuropharm.2025.110604; |
| G, ł, ombik K, Kukla-Bartoszek M, Suski M, Curzytek K, Grygier B, Basta-Kaim A, Comparative effectiveness of moderate treadmill training and venlafaxine treatment on long-lasting brain changes induced by prenatal dexamethasone exposure. Neuropharmacology, 279():110604(2025) [pubmed] |
Keyword List
| submitter keyword: frontal cortex, depression,rat, dexamethasone, anxiety |
Contact List
| Maciej Suski |
|---|
| contact affiliation | Department of Pharmacology Faculty of Medicine Jagiellonian University Medical College Krakow, Poland |
| contact email | maciej.suski@uj.edu.pl |
| lab head | |
| Maciej Suski |
|---|
| contact affiliation | Chair of Pharmacology |
| contact email | maciej.suski@uj.edu.pl |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/03/PXD063194 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD063194
- Label: PRIDE project
- Name: Treadmill training and venlafaxine treatment on brain changes induced by prenatal dexamethasone.
