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PXD063095-1

PXD063095 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleIdentifying putative substrates of Lon protease in Pseudomonas aeruginosa
DescriptionWe aim to identify potential substrates of the Lon protease in P. aeruginosa. Samples with the lon protease overexpressed or deleted were compared to the wild type to observe the proteins whose steady-state levels changed with change in Lon levels. We used spectinomycin to inhibit protein synthesis and observed the stability of proteins over 30 and 60 minutes to identify proteins whose stability also changed in response of Lon levels.
HostingRepositoryPRIDE
AnnounceDate2025-06-13
AnnouncementXMLSubmission_2025-06-13_06:28:09.837.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterGeorgios Mermelekas
SpeciesList scientific name: Bacteria; NCBI TaxID: NCBITaxon:2; scientific name: Pseudomonas aeruginosa PA1; NCBI TaxID: 1279007;
ModificationListmonohydroxylated residue; iodoacetamide derivatized residue
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-04-17 23:55:53ID requested
12025-06-13 06:28:10announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: proteomics, Lon protease,bacteria, Pseudomonas aeruginosa, substrates
Contact List
Kristina Jonas
contact affiliationStockholm University, Sweden
contact emailkristina.jonas@su.se
lab head
Georgios Mermelekas
contact affiliationKarolinska Institutet
contact emailgeorgios.mermelekas@scilifelab.se
dataset submitter
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Dataset FTP location
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