PXD063016-1

PXD063016 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	THP-1 macrophage ubiquitinome after Mtb infection
Description	Mycobacterium tuberculosis (Mtb) is the causative agent of tuberculosis (TB), capable of manipulating and circumventing the host's immune system to establish infection. Ubiquitination plays a crucial role in the host's response to pathogens; however, the global alterations in protein ubiquitination during Mtb infection remain poorly understood. To elucidate the regulatory roles of ubiquitination in the immune response to Mtb, we investigated the ubiquitome of human macrophages following Mtb infection.
HostingRepository	PRIDE
AnnounceDate	2025-08-21
AnnouncementXML	Submission_2025-08-21_05:58:42.629.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Qishun Feng
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	ubiquitination signature dipeptidyl lysine
Instrument	Orbitrap Astral

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-04-16 02:13:04	ID requested
⏵ 1	2025-08-21 05:58:43	announced

Publication List

10.3389/FMOLB.2025.1613454;

10.3389/FMOLB.2025.1613454;

Keyword List

submitter keyword: ubiquitinome,THP-1 macrophage, Mycobacterium tuberculosis infection

submitter keyword: ubiquitinome,THP-1 macrophage, Mycobacterium tuberculosis infection

Contact List

Qishun Feng
contact affiliation	National Clinical Research Center for Infectious Diseases, Shenzhen Third People's Hospital, Southern University of Science and Technology, Shenzhen
contact email	fengqs2013@163.com
lab head
Qishun Feng
contact affiliation	National Clinical Research Center for Infectious Diseases, Shenzhen Third People’s Hospital, Southern University of Science and Technology
contact email	fengqs2013@163.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/08/PXD063016
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/08/PXD063016

PRIDE project URI

Repository Record List

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