PXD062993-1

PXD062993 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Inhibition of fusidic acid resistance through restricting conformational flexibility in domain III of EF-G
Description	HDX-MS was used to study the binding of FusB to EF-G variants.
HostingRepository	PRIDE
AnnounceDate	2025-12-15
AnnouncementXML	Submission_2025-12-14_18:54:26.834.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Antonio Calabrese
SpeciesList	scientific name: Staphylococcus aureus; NCBI TaxID: NEWT:1280;
ModificationList	No PTMs are included in the dataset
Instrument	Synapt MS

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-04-15 10:35:00	ID requested
⏵ 1	2025-12-14 18:54:28	announced

Publication List

10.1073/pnas.2508779122;
Schindl A, Jones ME, Ghimire L, Kalverda AP, Wildsmith G, Calabrese AN, Tomlinson JH, Inhibition of fusidic acid resistance through restricting conformational flexibility in domain III of EF-G. Proc Natl Acad Sci U S A, 122(48):e2508779122(2025) [pubmed]

10.1073/pnas.2508779122;

Schindl A, Jones ME, Ghimire L, Kalverda AP, Wildsmith G, Calabrese AN, Tomlinson JH, Inhibition of fusidic acid resistance through restricting conformational flexibility in domain III of EF-G. Proc Natl Acad Sci U S A, 122(48):e2508779122(2025) [pubmed]

Keyword List

submitter keyword: FusB,EF-G

submitter keyword: FusB,EF-G

Contact List

Antonio Calabrese
contact affiliation	Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, United Kingdom
contact email	a.calabrese@leeds.ac.uk
lab head
Antonio Calabrese
contact affiliation	School of Molecular and Cellular Biology, University of Leeds
contact email	a.calabrese@leeds.ac.uk
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/12/PXD062993
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/12/PXD062993

PRIDE project URI

Repository Record List

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