PXD062856-1

PXD062856 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	LC-MS/MS-based profiling of REIIBP-mediated methylation substrates within the nucleolus
Description	Since REIIBP contains a complete SET domain and is associated with pre-rRNA processing factors in the nucleolus, we ask if REIIBP may methylate pre-rRNA processing factors in the nucleolus.To investigate this, we conducted LC-MS/MS analysis to identify potential protein substrates for methylation.
HostingRepository	PRIDE
AnnounceDate	2025-10-06
AnnouncementXML	Submission_2025-10-05_16:22:36.258.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	倩倩杨
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationList	monomethylated residue; N6; dimethylated residue
Instrument	timsTOF Pro 2

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-04-11 08:23:05	ID requested
⏵ 1	2025-10-05 16:22:37	announced

Publication List

10.1016/j.jbc.2025.110609;
Yang Q, Yu X, REIIBP methylates nucleolar proteins and regulates pre-rRNA processing. J Biol Chem, 301(10):110609(2025) [pubmed]

10.1016/j.jbc.2025.110609;

Yang Q, Yu X, REIIBP methylates nucleolar proteins and regulates pre-rRNA processing. J Biol Chem, 301(10):110609(2025) [pubmed]

Keyword List

submitter keyword: Hela cells, REIIBP， methylation

submitter keyword: Hela cells, REIIBP， methylation

Contact List

Xiaochun Yu
contact affiliation	Westlake University
contact email	yuxiaochun@westlake.edu.cn
lab head
倩倩杨
contact affiliation	Westlake university
contact email	yangqianqian@westlake.edu.cn
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/10/PXD062856
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/10/PXD062856

PRIDE project URI

Repository Record List

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