PXD062787-1

PXD062787 is an original dataset announced via ProteomeXchange.

Title	Proteomic Profiling of BCAA and BCKA Supplementation on Hepatic Lipid Metabolism in Primary Bovine Hepatocytes Under High Fatty Acid Conditions: Mechanistic Insights and Identification of Key Regulatory Pathways
Description	In this study, we employed quantitative proteomics and molecular docking to elucidate the differential hepatic responses to BCAA and BCKA supplementation in primary bovine hepatocytes exposed to physiologically high fatty acid conditions.
HostingRepository	PRIDE
AnnounceDate	2025-06-19
AnnouncementXML	Submission_2025-06-19_12:53:04.200.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD062787
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Jayasimha rayalu DADDAM
SpeciesList	scientific name: Bos taurus (Bovine); NCBI TaxID: 9913;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2025-04-09 11:50:39	ID requested
⏵ 1	2025-06-19 12:53:04	announced

10.6019/PXD062787;

submitter keyword: BCAA,Bovine, BCKA, Hepatocytes, Proteomics, LC-MS/MS

Zheng Zhou
contact affiliation	Department of Animal Sciences, Michigan State University, East Lansing, USA
contact email	zhouzz@msu.edu
lab head
Jayasimha rayalu DADDAM
contact affiliation	Department of Animal Sciences, Michigan State University
contact email	daddamj1@msu.edu
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD062787
     1. Label: PRIDE project
     2. Name: Proteomic Profiling of BCAA and BCKA Supplementation on Hepatic Lipid Metabolism in Primary Bovine Hepatocytes Under High Fatty Acid Conditions: Mechanistic Insights and Identification of Key Regulatory Pathways