PXD062616-1

PXD062616 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	NRBP1 pseudokinase binds to and activates the WNK pathway in response to osmotic stress - Figure 1D/S1C
Description	Please refer to the manuscript for a detailed description.
HostingRepository	PRIDE
AnnounceDate	2025-07-21
AnnouncementXML	Submission_2025-07-20_17:13:13.203.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Frederic Lamoliatte
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Astral

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-04-04 09:15:40	ID requested
⏵ 1	2025-07-20 17:13:14	announced

Publication List

10.1126/sciadv.adv4636;
Amnekar RV, Dite T, Lis P, Bell S, Brown F, Johnson C, Wilkinson S, Raggett S, Dorward M, Wightman M, Macartney T, Soares RF, Lamoliatte F, Alessi DR, NRBP1 pseudokinase binds to and activates the WNK pathway in response to osmotic stress. Sci Adv, 11(29):eadv4636(2025) [pubmed]

10.1126/sciadv.adv4636;

Amnekar RV, Dite T, Lis P, Bell S, Brown F, Johnson C, Wilkinson S, Raggett S, Dorward M, Wightman M, Macartney T, Soares RF, Lamoliatte F, Alessi DR, NRBP1 pseudokinase binds to and activates the WNK pathway in response to osmotic stress. Sci Adv, 11(29):eadv4636(2025) [pubmed]

Keyword List

submitter keyword: osmotic stress, WNK pathway,NRBP1 pseudokinase

submitter keyword: osmotic stress, WNK pathway,NRBP1 pseudokinase

Contact List

Dario R. Alessi
contact affiliation	Medical Research Council (MRC) Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK
contact email	d.r.alessi@dundee.ac.uk
lab head
Frederic Lamoliatte
contact affiliation	University of Dundee
contact email	flamoliatte001@dundee.ac.uk
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/07/PXD062616
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/07/PXD062616

PRIDE project URI

Repository Record List

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