PXD062417 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Immunoprecipitation-Mass Spectrometry (IP-MS) of SRPK1 in endothelial cells |
| Description | To identify the E3 ubiquitin ligase responsible for the polyubiquitination of SRPK1, we performed immunoprecipitation (IP) using an anti-SRPK1 antibody or IgG control as well as endothelial lysates treated with PA and MG-132, followed by mass spectrometry analysis |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-05-30 |
| AnnouncementXML | Submission_2026-05-29_19:43:17.984.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Xiao-Hui Tan |
| SpeciesList | scientific name: Rattus norvegicus (Rat); NCBI TaxID: NEWT:10116; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive HF |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-03-31 09:13:16 | ID requested | |
| ⏵ 1 | 2026-05-29 19:43:18 | announced | |
Publication List
| Tan XH, Li KF, Yuan YM, Xia MC, Zhao FZ, Ying HG, Zhou Z, Gao PC, Xie GQ, Li XS, Jiang H, Guan RL, Palmitoylation-Mediated Ubiquitination of SRPK1 Regulates Ferroptosis in High-Fat-Induced Erectile Dysfunction. Adv Sci (Weinh), 13(19):e13796(2026) [pubmed] |
| 10.1002/advs.202513796; |
Keyword List
| submitter keyword: rat, endothelial cells, LC-MS/MS |
Contact List
| Rui-Li GUAN |
|---|
| contact affiliation | Peking University First Hospital |
| contact email | guanruili@bjmu.edu.cn |
| lab head | |
| Xiao-Hui Tan |
|---|
| contact affiliation | Peking University First Hospital |
| contact email | brendan0535@dingtalk.com |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/05/PXD062417 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD062417
- Label: PRIDE project
- Name: Immunoprecipitation-Mass Spectrometry (IP-MS) of SRPK1 in endothelial cells
