PXD062315-1

PXD062315 is an original dataset announced via ProteomeXchange.

Title	Cohesin interacting partners before and after DSB induction
Description	Here we made use of a human osteosarcoma U-2 OS modified cell line (U-2 OS DIvA- Flag-GFP-SMC1), expressing a hydroxytamoxifen controlled restriction enzyme (AsiSI-ER which allows the induction of multiple annotated DSBs) and Flag GFP-SMC. We performed tandem purification before and after DSB induction followed by mass spectrometry to identify cohesin interacting partners.
HostingRepository	PRIDE
AnnounceDate	2025-04-29
AnnouncementXML	Submission_2025-04-29_05:00:36.620.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Alexandre STELLA
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iodoacetamide derivatized residue
Instrument	LTQ Orbitrap Velos

Revision	Datetime	Status	ChangeLog Entry
0	2025-03-27 09:15:41	ID requested
⏵ 1	2025-04-29 05:00:37	announced

Dataset with its publication pending

submitter keyword: LC-MSMS, human osteosarcoma cell,Cohesin, DSB

Odile Burlet-Schiltz
contact affiliation	Proteomics Facility of Toulouse, ProteoToul Services Proteomics French Infrastructure, ProFI IPBS, CNRS, UMR 5089
contact email	Odile.Schiltz@ipbs.fr
lab head
Alexandre STELLA
contact affiliation	CNRS
contact email	alexandre.stella@ipbs.fr
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/04/PXD062315

PRIDE project URI

• PRIDE
  1. PXD062315
     1. Label: PRIDE project
     2. Name: Cohesin interacting partners before and after DSB induction