PXD062250-2

PXD062250 is an original dataset announced via ProteomeXchange.

Title	Identify the host factors interacting with ZIKV NS4B
Description	To identify the host factors involved in NS4B-induced PD-L1 upregulation, we conducted mass spectrometric analysis to identify potential binding partners of NS4B.
HostingRepository	PRIDE
AnnounceDate	2025-09-22
AnnouncementXML	Submission_2025-09-22_06:53:47.398.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Chenxi Wang
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2025-03-26 00:48:25	ID requested
1	2025-08-29 20:50:04	announced
⏵ 2	2025-09-22 06:53:48	announced	2025-09-22: Updated project metadata.

10.1371/journal.ppat.1013457;

Wang C, Xie Y, Li W, Ong CP, Ding H, Yuan S, Cheng G, Jin DY, Ye ZW, Activation of PD-1/PD-L1 immune checkpoint by Zika virus. PLoS Pathog, 21(9):e1013457(2025) [pubmed]

submitter keyword: ZIKV, NS4B, binding proteins

Dong-Yan Jin
contact affiliation	School of Biomedical Sciences, The University of Hong Kong
contact email	dyjin@hku.hk
lab head
Chenxi Wang
contact affiliation	University of Hong Kong
contact email	ccxx1101@hku.hk
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/08/PXD062250

PRIDE project URI

• PRIDE
  1. PXD062250
     1. Label: PRIDE project
     2. Name: Identify the host factors interacting with ZIKV NS4B