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PXD062186-1

PXD062186 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteomics-based study on the protective effect and mechanism of Inkslan on type 2 diabetes mouse model through transcription growth factor β pathway
DescriptionTo determine whether the novel Proprotein Convertase Subtilisin/Kexin Type 9(PCSK9-RRB- inhibitor inkslan has renal protective effects in high glucose environments, we tested the effectsInkslanslan on renal function in rats, proteomics technology was used to predict whether its effects were related through the Transforming Growth Factor-β (TGF-β) pathway, and to construct its regulatory network. The Transforming Growth Factor of Transforming Growth Factor-β (TGF-β) pathway was analyzed
HostingRepositoryiProX
AnnounceDate2025-03-24
AnnouncementXMLSubmission_2025-03-24_19:34:02.237.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterHongqian Li
SpeciesList scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationListNo PTMs are included in the dataset
InstrumenttimsTOF Pro
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-03-24 19:33:38ID requested
12025-03-24 19:34:02announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Proprotein convertase subtilisin-9, diabetic nephropathy, transcription growth factor beta, proteomics
Contact List
Weihua Wu
contact affiliationSouthwest Medical University Hospital
contact email2390369@qq.com
lab head
Hongqian Li
contact affiliationSouthwest Medical University Hospital
contact emaillhq1693644838@163.com
dataset submitter
Full Dataset Link List
iProX dataset URI