PXD062155-2
PXD062155 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Si-pgc-1 α LNP prevents bladder cancer metastasis by inhibiting mitochondrial biogenesis and energy metabolism in cancer cells |
| Description | This study aims to explore the effect of PGC-1 α siRNA delivered by liposomal nanoparticles on cancer cells through transcriptome, proteome and metabolome technologies, so as to reveal its regulatory effect on cancer cell reprogramming and energy metabolism, so as to provide clues for the molecular mechanism of the treatment of metastatic bladder cancer. |
| HostingRepository | iProX |
| AnnounceDate | 2025-03-22 |
| AnnouncementXML | Submission_2025-07-08_22:50:19.759.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Zhenghua Liu |
| SpeciesList | scientific name: Mus musculus; NCBI TaxID: 10090; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | LTQ |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2025-03-23 20:06:26 | ID requested | |
| 1 | 2025-03-23 20:06:39 | announced | |
| ⏵ 2 | 2025-07-08 22:50:20 | announced | 2025-07-09: Add info. |
Publication List
| Liu Z, Xin P, Wu W, Jin M, Du Y, Jiang Y, Liu T, Zhang H, reveals critical metabolic pathways in bladder cancer metastasis. Commun Biol, 8(1):788(2025) [pubmed] |
Keyword List
| submitter keyword: PGC-1α |
Contact List
| Hao Zhang | |
|---|---|
| contact affiliation | The First Hospital of China Medical University |
| contact email | Lunar8511@126.com |
| lab head | |
| Zhenghua Liu | |
| contact affiliation | The First Hospital of China Medical University |
| contact email | 1545559471@qq.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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