PXD061959-2

PXD061959 is an original dataset announced via ProteomeXchange.

Title	the MS data involved in the article "Nuclear ACAT1 orchestrates natural killer cell-dependent antitumor immunity in colorectal cancer"
Description	In this study we aim to explore the metabolic enzyme that affects NK cell function in colorectal cancer, and mainly focus on the mechanism how nuclear ACAT1（Mitochondrial acetyl-CoA acetyltransferase）promotes NK cell infiltration and activation
HostingRepository	iProX
AnnounceDate	2025-03-18
AnnouncementXML	Submission_2025-05-19_00:20:19.274.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Chen Wei
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2025-03-18 00:00:42	ID requested
1	2025-03-31 19:42:43	announced
⏵ 2	2025-05-19 00:20:20	announced	2025-05-19: Add Publication.

Wei C, Liao K, Chen HJ, Xiao ZX, Meng Q, Liu ZK, Lu YX, Sheng H, Mo HY, Wu QN, Han Y, Zeng ZL, Guan XY, Luo HY, Ju HQ, Xu RH, Nuclear mitochondrial acetyl-CoA acetyltransferase 1 orchestrates natural killer cell-dependent antitumor immunity in colorectal cancer. Signal Transduct Target Ther, 10(1):138(2025) [pubmed]

submitter keyword: Cancer metabolism, Cancer immunology, NK cell immunity, ACAT1, Colorectal cancer

Ruihua Xu
contact affiliation	Sun Yat-sen University Cancer Center
contact email	xurh@sysucc.org.cn
lab head
Chen Wei
contact affiliation	Sun Yat-sen University Cancer Center
contact email	weichen@sysucc.org.cn
dataset submitter

iProX dataset URI