PXD061948-2

PXD061948 is an original dataset announced via ProteomeXchange.

Title	Deciphering aging-related changes based on cross-tissue proteomic profilling
Description	The project aims to investigate the molecular mechanisms of aging by analyzing protein expression and modifications across various tissues in multiple organisms. Using advanced mass spectrometry, the project will collect and compare proteomic profiles from different organs at various ages. By identifying unique and shared aging-related biomarkers and pathways, the project seeks to enhance our understanding of the aging process and its impact on health. Ultimately, this research may pave the way for developing targeted therapies to improve healthspan and combat age-related diseases.
HostingRepository	iProX
AnnounceDate	2025-03-18
AnnouncementXML	Submission_2025-07-08_23:02:16.591.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Feng Zhang
SpeciesList	scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	timsTOF Pro

Revision	Datetime	Status	ChangeLog Entry
0	2025-03-17 21:03:18	ID requested
1	2025-03-17 21:03:44	announced
⏵ 2	2025-07-08 23:02:17	announced	2025-07-09: Add info.

Zhang F, Li R, Liu Y, Liang J, Gong Y, Xiao C, Cai J, Wang T, You Q, Zhang J, Chen H, Xiao J, Zhang Y, Yang Y, Li H, Yao J, Zhang Q, Zheng J, Integrative cross-tissue analysis unveils complement-immunoglobulin augmentation and dysbiosis-related fatty acid metabolic remodeling during mammalian aging. Imeta, 4(3):e70027(2025) [pubmed]

submitter keyword: aging, cross-tissue

Jun Zheng
contact affiliation	Third Affiliated Hospital of Sun Yat-sen University
contact email	zhengj67@mail2.sysu.edu.cn
lab head
Feng Zhang
contact affiliation	Third Affiliated Hospital of Sun Yat-sen University
contact email	jenverzhang@163.com
dataset submitter

iProX dataset URI