PXD061689-1

PXD061689 is an original dataset announced via ProteomeXchange.

Title	SDC4 drives fibrotic remodeling of the intervertebral disc under altered spinal loading
Description	In this study, we study protein expression profiles in Sdc4-deleted NP cells under mechanical loading and natural physiological loading.
HostingRepository	PRIDE
AnnounceDate	2025-10-13
AnnouncementXML	Submission_2025-10-12_17:28:41.805.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Kimheak Sao
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Astral

Revision	Datetime	Status	ChangeLog Entry
0	2025-03-11 03:14:36	ID requested
⏵ 1	2025-10-12 17:28:43	announced

Sao K, Risbud MV, SDC4 drives fibrotic remodeling of the intervertebral disc under altered spinal loading. Cell Death Dis, 16(1):678(2025) [pubmed]

10.1038/s41419-025-08002-3;

submitter keyword: Syndecan 4, Nucleus pulposus,Proteomic, SDC4, Intervertebral disc

Makarand V.
contact affiliation	Thomas Jefferson University
contact email	Makarand.Risbud@jefferson.edu
lab head
Kimheak Sao
contact affiliation	Thomas jefferson University
contact email	kxs489@students.jefferson.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/10/PXD061689

PRIDE project URI

• PRIDE
  1. PXD061689
     1. Label: PRIDE project
     2. Name: SDC4 drives fibrotic remodeling of the intervertebral disc under altered spinal loading