PXD061534 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Queuosine-modified tRNA influences differentiation of Leishmania mexicana by codon bias translation |
| Description | Using quantitative proteomics, we aim to compare the total proteome of L. mexicana wild (WT), knock-out (KO) and addback. The protein profile of all three will be related at five separate time points of life cycle differentiation. The objective is to elucidate the impact of Q-tRNA depletion on cellular proteome during differentiation. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-06-04 |
| AnnouncementXML | Submission_2026-06-03_16:41:19.578.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Pavel Roudnický |
| SpeciesList | scientific name: Leishmania mexicana; NCBI TaxID: NEWT:5665; |
| ModificationList | iodoacetamide derivatized residue |
| Instrument | timsTOF Pro 2 |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
| 0 | 2025-03-06 09:21:04 | ID requested | |
| ⏵ 1 | 2026-06-03 16:41:20 | announced | |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Leishmania Mexicana, proteomics, Queuosine, differentiation, timsTOF, translation |
Contact List
| Zbynek Zdrahal |
| contact affiliation | Proteomics Core Facility and Research Group Proteomics, CEITEC-MU, Masaryk University, Brno, Czech Republic |
| contact email | zdrahal@sci.muni.cz |
| lab head | |
| Pavel Roudnický |
| contact affiliation | Masaryk University |
| contact email | p.roudnicky@mail.muni.cz |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
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| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD061534
- Label: PRIDE project
- Name: Queuosine-modified tRNA influences differentiation of Leishmania mexicana by codon bias translation