⮝ Full datasets listing
PXD061478-1
PXD061478 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Affinity-based protein profiling of benzodiazepine targets in rat synaptosomes |
| Description | Three affinity-based probes based on the benzodiazepines flurazepam and flunitrazepam were synthesized and applied to identify benzodiazepine-binding proteins in synaptosomes derived from rat brain tissue. Proteins were obtained from brain tissue through homogenization and ultracentrifugation, labeled with the probes in the presence and absence of authentic flurazepam, enriched on streptavidin beads and digested, then analyzed by LC-MS/MS. Data was searched with MS-GF+ using PNNL's DMS processing pipeline. |
| HostingRepository | MassIVE |
| AnnounceDate | 2026-03-11 |
| AnnouncementXML | Submission_2026-03-11_17:39:49.834.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Non peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Supported dataset by repository |
| PrimarySubmitter | Matthew Monroe |
| SpeciesList | scientific name: Rattus norvegicus; common name: Norway rat; NCBI TaxID: 10116; |
| ModificationList | Carbamidomethyl; Oxidation |
| Instrument | Q Exactive Plus |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2025-03-04 18:07:06 | ID requested | |
| ⏵ 1 | 2026-03-11 17:39:50 | announced |
Publication List
| no publication |
Keyword List
| submitter keyword: affinity-based protein profiling, benzodiazepine, DatasetType:Proteomics |
Contact List
| Vivian Lin | |
|---|---|
| contact affiliation | Pacific Northwest National Laboratory |
| contact email | vivian.lin@pnnl.gov |
| lab head | |
| Matthew Monroe | |
| contact affiliation | Pacific Northwest National Laboratory |
| contact email | matthew.monroe@pnnl.gov |
| dataset submitter | |
Full Dataset Link List
| MassIVE dataset URI |
| Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive-ftp.ucsd.edu/v09/MSV000097238/ |
