PXD061429 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Protein-agnostic pulldown of brain-derived aggregates from Motor Neuron Disease |
| Description | Characterisation of homognised BA tissue extracts from TDP-43 MND (×5), SOD1-MND (×2) and neurologically normal controls (×3) using the protein-agnostic aggregate probe CAP1. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-02-03 |
| AnnouncementXML | Submission_2026-02-02_20:15:07.299.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Dezerae Cox |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | iodoacetamide derivatized residue |
| Instrument | Orbitrap Fusion Lumos |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-03-03 21:47:07 | ID requested | |
| ⏵ 1 | 2026-02-02 20:15:08 | announced | |
Publication List
| 10.1002/advs.202505484; |
| Cox D, Burke M, Milani S, White MA, Waldron FM, B, ö, ken D, Lobanova E, Sreedharan J, Gregory JM, Klenerman D, Quantitative Profiling of Nanoscopic Protein Aggregates Reveals Specific Fingerprint of TDP-43-Positive Assemblies in Motor Neuron Disease. Adv Sci (Weinh), 12(44):e05484(2025) [pubmed] |
Keyword List
| submitter keyword: Human, aggregate, ALS, MND |
Contact List
| Prof. Sir David Klenerman |
|---|
| contact affiliation | UK Dementia Research Institute Department of Chemistry University of Cambridge, UK |
| contact email | dk10012@cam.ac.uk |
| lab head | |
| Dezerae Cox |
|---|
| contact affiliation | Molecular Horizons, University of Wollongong |
| contact email | dezerae@uow.edu.au |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/02/PXD061429 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD061429
- Label: PRIDE project
- Name: Protein-agnostic pulldown of brain-derived aggregates from Motor Neuron Disease
