PXD061388-1

PXD061388 is an original dataset announced via ProteomeXchange.

Title	Global proteomic responses of Escherichia coli, Klebsiella pneumoniae, Enterococcus faecium and Staphylococcus aureus to sub-inhibitory concentrations of antibiotics using LC-MS/MS analysis
Description	The objective of this study was to analyse proteomic profiles of antibiotic-susceptible E. coli MG1655, K. pneumoniae NCTC418, E. faecium NCTC13169, and S. aureus NCTC8325 under sub-inhibitory antibiotic stress. Gram-negative bacteria were exposed to cefotaxime, ciprofloxacin, kanamycin, and imipenem, while Gram-positive bacteria were treated with chloramphenicol, vancomycin, or oxacillin.
HostingRepository	PRIDE
AnnounceDate	2025-09-22
AnnouncementXML	Submission_2025-09-21_16:46:46.543.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Monika Subanovic
SpeciesList	scientific name: Escherichia coli; NCBI TaxID: 562; scientific name: Klebsiella pneumoniae; NCBI TaxID: 573; scientific name: Bacteria; NCBI TaxID: NCBITaxon:2; scientific name: Enterococcus faecium; NCBI TaxID: 1352; scientific name: Staphylococcus aureus; NCBI TaxID: 1280;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2025-03-03 03:48:04	ID requested
⏵ 1	2025-09-21 16:46:47	announced

10.1038/s44259-025-00147-7;

Subanovic M, Frawley D, Tierney C, Velasco-Torrijos T, Walsh F, Proteomic and metabolomic responses of priority bacterial pathogens to subinhibitory concentration of antibiotics. NPJ Antimicrob Resist, 3(1):80(2025) [pubmed]

submitter keyword: Escherichia coli, Klebsiella pneumoniae, Staphylococcus aureus, antibiotic, Enterococcus faecium

Prof. Fiona Walsh
contact affiliation	Biology department, Maynooth University, Republic of Ireland
contact email	fiona.walsh@mu.ie
lab head
Monika Subanovic
contact affiliation	Maynooth University
contact email	monika.subanovic@mu.ie
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/09/PXD061388

PRIDE project URI

• PRIDE
  1. PXD061388
     1. Label: PRIDE project
     2. Name: Global proteomic responses of Escherichia coli, Klebsiella pneumoniae, Enterococcus faecium and Staphylococcus aureus to sub-inhibitory concentrations of antibiotics using LC-MS/MS analysis