⮝ Full datasets listing
PXD061372-1
PXD061372 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | RIPK2 promotes colorectal cancer metastasis by protecting YAP degradation from ITCH-mediated ubiquitination |
| Description | Colorectal cancer (CRC) is a leading cause of cancer death. RIPK2 is identified as a poor prognostic marker, promoting metastasis via bacterial invasion. High RIPK2-expressing tumor cells show enhanced invasiveness. This dataset comprises quantitative proteomic profiles of colorectal cancer (CRC) cells comparing non-targeting control (NC) and RIPK2-knockdown (KD) groups. |
| HostingRepository | iProX |
| AnnounceDate | 2025-03-03 |
| AnnouncementXML | Submission_2025-10-30_17:44:04.303.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Chunzhao Yu |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | iodoacetamide derivatized residue; methionine oxidation with neutral loss of 64 Da |
| Instrument | Q Exactive HF-X |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2025-03-02 20:11:16 | ID requested | |
| ⏵ 1 | 2025-10-30 17:44:05 | announced |
Publication List
| Lu C, Liu H, Liu T, Sun S, Zheng Y, Ling T, Luo X, E Y, Xu Y, Li J, Liu L, Miao L, Liu Z, Yu C, RIPK2 promotes colorectal cancer metastasis by protecting YAP degradation from ITCH-mediated ubiquitination. Cell Death Dis, 16(1):248(2025) [pubmed] |
Keyword List
| submitter keyword: RIPK2, Proteomics, colorectal cancer |
Contact List
| Chunzhao Yu | |
|---|---|
| contact affiliation | Nanjing Medical University |
| contact email | chunzhaoyu@njmu.edu.cn |
| lab head | |
| Chunzhao Yu | |
| contact affiliation | Nanjing Medical University |
| contact email | chunzhaoyu@njmu.edu.cn |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
